Fortiflora
Nº1 in scientific studies

Behind its active strain SF681, among all strains approved in EU for dogs and cats.
1Enterococcus faecium NCIMB 10415 (4b1705) - SF68

Meet the scientists

The science behind FortiFlora®. Interview with Dr. Gail Czarnecki-Maulden, Ph.D.

1 Enterococcus faecium NCIMB 10415 (4b1705) – SF68

2 Among all strains approved in EU for dogs and cats

PRO PLAN® FortiFlora®. Outstanding results in the spotlight:

Supplementation of food with Enterococcus faecium (SF68®) stimulates immune functions in young dogs. (Benyacoub J et al. 2003)1 Download Study
  • Dogs fed with E. faecium SF68 4b1705 showed enhanced immune function and a strengthened specific immune function, with a significant increase in CDV virus specific IgG and IgA levels in response to vaccination.
  • The puppies fed SF68 maintained CDV specific immunoglobins longer than did the control puppies.

1 Benyacoub J, Czarnecki- Maulden G, Cavadini C, et al. 2003. Supplementation of food with Enterococcus faecium (SF68®) stimulates immune functions in young dogs. J Nutr. 133 (4). 1158- 1162.

Effect of supplementation with Enterococcus faecium (SF68®) on immune functions in cats. (Veir JK, et al. 2007)2 Link to article
  • Results showing that the percentage of CD4+ lymphocytes was significantly higher in cats supplemented with E.faecium SF68 – indicative of positive immune function.

2Veir JK, Knorr R, Cavadini C, et al. 2007. Effect of supplementation with Enterococcus faecium (SF68®) on immune functions in cats. Vet Therap. 8: 4, 229- 238

Effect of the probiotic Enterococcus faecium SF68 on presence of diarrhoea in cats and dogs housed in an animal shelter. (Bybee SN et al. 2011)3 Link to article
  • Cats supplemented with E. faecium SF68 4b1705 had fewer episodes of diarrhoea than the control group.

3Bybee SN, Scorza AV, Lappin MR. 2011. Effect of the probiotic Enterococcus faecium SF68 on presence of diarrhoea in cats and dogs housed in an animal shelter. J Vet Intern Med. 25:856–8602.

Effects of Enterococcus faecium on stress diarrhoea. (Gore AM and Reynolds A. 2012)4 Link to article
  • A study was carried out to look at the effect of E. faecium SF68 4b1705 on stress diarrhoea in Alaskan sled dogs
  • It was seen that dogs supplemented with E. faecium SF68 4b1705 experienced significantly fewer days with severe diarrhoea and improved faster than dogs in the placebo group.

4Gore AM, Reynolds A. 2012. Effects of Enterococcus faecium on stress diarrhoea. ACVIM Forum Proceedings. p 453.

Evaluation of metronidazole with and without Enterococcus faecium SF68 in shelter dogs with diarrhoea. (Fenimore A et al. 2017)5 Link to article
  • Results showed that the addition of E. faecium SF68 4b1705 to the protocol appeared to enhance clinical responses in dogs with diarrhoea.

5Fenimore A, Martin L, Lappin MR. 2017. Evaluation of metronidazole with and without Enterococcus faecium SF68 in shelter dogs with diarrhoea. Topics in Compan An Med. (32)100–103

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